HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)
Gene: MAP1LC3B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	33545068, 20562859
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005874 - microtubule GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 125
+	Hs
		933963 TBB4B_HUMAN (1-427): 0: 707: 98.36		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		1046570 TBB2A_HUMAN (1-430): 0: 704: 96.98		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		428428 TBB5_HUMAN (1-429): 0: 709: 100.00		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		306159 TBB3_HUMAN (1-444): 0: 712: 92.57		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		933972 TBB4B_HUMAN (1-427): 0: 707: 98.36		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		428116 TBB5_HUMAN (1-429): 0: 709: 100.00		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		1046576 TBB2A_HUMAN (1-430): 0: 704: 96.98		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		305904 TBB5_HUMAN (1-429): 0: 709: 100.00		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		891070 TBB4B_HUMAN (1-427): 0: 707: 98.36		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		306099 TBB4B_HUMAN (1-427): 0: 707: 98.36		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		428423 TBB5_HUMAN (1-429): 0: 709: 100.00		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		306165 TBB2A_HUMAN (1-430): 0: 704: 96.98		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		933967 TBB4B_HUMAN (1-427): 0: 707: 98.36		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		305889 TBB4A_HUMAN (1-427): 0: 702: 97.42		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30