HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: TSP50 (Q9UI38)
Probable threonine protease PRSS50 (EC 3.4.25.-) (Cancer/testis antigen 20) (Serine protease 50) (Testis-specific protease-like protein 50)
Gene: PRSS50

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 444 Hs			1 385
+	Hs
		1037431 TBB3_HUMAN (1-444): 0: 712: 92.57		TSP50_HUMAN (1-370): 8.52e-137: 397: 100.00
+	Hs
		341273 TBB3_HUMAN (1-444): 0: 712: 92.57		FA9_HUMAN (36-358): 2.36e-97: 299: 25.37
+	Hs
		428722 TBB3_HUMAN (1-444): 0: 712: 92.57		TRY2_HUMAN (112-361): 5.53e-100: 298: 25.10
+	Hs
		589992 TBB3_HUMAN (1-444): 0: 712: 92.57		TRYB2_HUMAN (102-354): 4.66e-99: 297: 30.89
+	Hs
		381216 TBB4A_HUMAN (1-427): 0: 702: 97.42		PRSS8_HUMAN (104-357): 7.27e-102: 306: 32.69
+	Hs
		1037390 TBB3_HUMAN (1-444): 0: 712: 92.57		TMPS5_HUMAN (77-362): 1.66e-95: 294: 26.28
+	Hs
		428014 TBB5_HUMAN (1-429): 0: 709: 100.00		TRYB2_HUMAN (102-354): 4.66e-99: 297: 30.89
+	Hs
		589991 TBB4B_HUMAN (1-427): 0: 707: 98.36		TRYB2_HUMAN (102-354): 4.66e-99: 297: 30.89
+	Hs
		589997 TBB2B_HUMAN (1-430): 0: 707: 97.44		TRYB2_HUMAN (102-354): 4.66e-99: 297: 30.89
+	Hs
		428427 TBB5_HUMAN (1-429): 0: 709: 100.00		TMPS5_HUMAN (77-362): 1.66e-95: 294: 26.28
+	Hs
		589993 TBB2A_HUMAN (1-430): 0: 704: 96.98		TRYB2_HUMAN (102-354): 4.66e-99: 297: 30.89
+	Hs
		933971 TBB4B_HUMAN (1-427): 0: 707: 98.36		TMPS5_HUMAN (77-362): 1.66e-95: 294: 26.28
+	Hs
		381121 TBB4A_HUMAN (1-427): 0: 702: 97.42		TRYB2_HUMAN (102-354): 4.66e-99: 297: 30.89
+	Hs
		589994 TBB8_HUMAN (1-427): 0: 702: 89.70		TRYB2_HUMAN (102-354): 4.66e-99: 297: 30.89
+	Hs
		1046575 TBB2A_HUMAN (1-430): 0: 704: 96.98		TMPS5_HUMAN (77-362): 1.66e-95: 294: 26.28
+	Hs
		1312808 TBB6_HUMAN (1-432): 0: 703: 92.13		TMPS5_HUMAN (77-362): 1.66e-95: 294: 26.28
+	Hs
		1114233 TBB8_HUMAN (1-427): 0: 702: 89.70		TMPS5_HUMAN (77-362): 1.66e-95: 294: 26.28
+	Hs
		1037277 TBB3_HUMAN (1-444): 0: 712: 92.57		PRS42_HUMAN (123-336): 1.15e-28: 115: 31.31
+	Hs
		1114117 TBB8_HUMAN (1-427): 0: 702: 89.70		PRS42_HUMAN (123-336): 1.15e-28: 115: 31.31
+	Mm
		371765 TBB4B_MOUSE (1-427): 0: 707: 98.36		CFAD_MOUSE (118-359): 4.81e-27: 109: 31.71