HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: MCM8 (Q9UJA3)
DNA helicase MCM8 (EC 3.6.4.12) (Minichromosome maintenance 8)
Gene: MCM8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 840
+	Hs
		832435 TBB3_HUMAN (1-444): 0: 712: 92.57		MCM2_HUMAN (33-824): 0: 728: 27.95
+	Hs
		428090 TBB5_HUMAN (1-429): 0: 709: 100.00		MCM2_HUMAN (33-824): 0: 728: 27.95
+	Hs
		832355 TBB4B_HUMAN (1-427): 0: 707: 98.36		MCM2_HUMAN (33-824): 0: 728: 27.95
+	Hs
		832688 TBB2B_HUMAN (1-430): 0: 707: 97.44		MCM2_HUMAN (33-824): 0: 728: 27.95
+	Hs
		832444 TBB2A_HUMAN (1-430): 0: 704: 96.98		MCM2_HUMAN (33-824): 0: 728: 27.95
+	Hs
		832684 TBB6_HUMAN (1-432): 0: 703: 92.13		MCM2_HUMAN (33-824): 0: 728: 27.95
+	Hs
		381148 TBB4A_HUMAN (1-427): 0: 702: 97.42		MCM2_HUMAN (33-824): 0: 728: 27.95
+	Hs
		708631 TBB3_HUMAN (1-444): 0: 712: 92.57		MCM5_HUMAN (66-822): 0: 708: 24.94
+	Hs
		428045 TBB5_HUMAN (1-429): 0: 709: 100.00		MCM5_HUMAN (66-822): 0: 708: 24.94
+	Hs
		708602 TBB4B_HUMAN (1-427): 0: 707: 98.36		MCM5_HUMAN (66-822): 0: 708: 24.94
+	Hs
		708756 TBB2B_HUMAN (1-430): 0: 707: 97.44		MCM5_HUMAN (66-822): 0: 708: 24.94
+	Hs
		708637 TBB2A_HUMAN (1-430): 0: 704: 96.98		MCM5_HUMAN (66-822): 0: 708: 24.94
+	Hs
		381132 TBB4A_HUMAN (1-427): 0: 702: 97.42		MCM5_HUMAN (66-822): 0: 708: 24.94