HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: KLK5 (Q9Y337)
Kallikrein-5 (EC 3.4.21.-) (Kallikrein-like protein 2) (KLK-L2) (Stratum corneum tryptic enzyme)
Gene: KLK5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 293
+	Hs
		1037451 TBB3_HUMAN (1-444): 0: 712: 92.57		KLK5_HUMAN (1-293): 8.79e-130: 372: 100.00
+	Hs
		934035 TBB4B_HUMAN (1-427): 0: 707: 98.36		KLK5_HUMAN (1-293): 8.79e-130: 372: 100.00
+	Hs
		1046624 TBB2A_HUMAN (1-430): 0: 704: 96.98		KLK5_HUMAN (1-293): 8.79e-130: 372: 100.00
+	Hs
		1312839 TBB6_HUMAN (1-432): 0: 703: 92.13		KLK5_HUMAN (1-293): 8.79e-130: 372: 100.00
+	Hs
		1114269 TBB8_HUMAN (1-427): 0: 702: 89.70		KLK5_HUMAN (1-293): 8.79e-130: 372: 100.00
+	Hs
		381331 TBB4A_HUMAN (1-427): 0: 702: 97.42		KLK5_HUMAN (1-293): 8.79e-130: 372: 100.00
+	Hs
		428722 TBB3_HUMAN (1-444): 0: 712: 92.57		TRY2_HUMAN (66-293): 4.58e-111: 322: 44.54
+	Hs
		1037427 TBB3_HUMAN (1-444): 0: 712: 92.57		KLK11_HUMAN (64-292): 2.13e-101: 299: 50.43
+	Hs
		1037334 TBB3_HUMAN (1-444): 0: 712: 92.57		KLK6_HUMAN (64-291): 1.92e-98: 290: 44.98
+	Hs
		420746 TBB8_HUMAN (1-427): 0: 702: 89.70		KLK1_HUMAN (50-293): 8.09e-100: 295: 37.35
+	Hs
		1114231 TBB8_HUMAN (1-427): 0: 702: 89.70		KLK15_HUMAN (57-292): 1.13e-97: 289: 40.08
+	Hs
		836354 TBB3_HUMAN (1-444): 0: 712: 92.57		GRAK_HUMAN (67-289): 2.63e-38: 137: 36.17
+	Hs
		381216 TBB4A_HUMAN (1-427): 0: 702: 97.42		PRSS8_HUMAN (51-289): 8.32e-35: 130: 35.63