HitPredict

Interactor 1: TRY1 (P07477)
Serine protease 1 (EC 3.4.21.4) (Anionic trypsin I) (Anionic trypsin-I) (Beta-trypsin) (Cationic trypsinogen) (Pretrypsinogen I) (Trypsin I) (Trypsin-1) [Cleaved into: Alpha-trypsin chain 1; Alpha-trypsin chain 2]
Gene: PRSS1

Interactor 2: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 247 Hs			1 654
+	Hs
		428712 TRY2_HUMAN (1-247): 2.77e-123: 352: 89.47		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		420734 KLK1_HUMAN (3-247): 3.42e-104: 304: 40.93		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		426506 KLK3_HUMAN (3-246): 9.02e-102: 298: 40.86		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		502706 KLK5_HUMAN (7-247): 4.57e-98: 289: 44.90		BIP_HUMAN (19-654): 0: 914: 100.00