HitPredict

Interactor 1: TRY2 (P07478)
Trypsin-2 (EC 3.4.21.4) (Anionic trypsinogen) (Serine protease 2) (Trypsin II)
Gene: PRSS2

Interactor 2: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 247 Hs			1 654
+	Hs
		428660 TRY1_HUMAN (1-247): 3.02e-133: 377: 89.47		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		420734 KLK1_HUMAN (3-247): 2.23e-104: 304: 40.93		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		426506 KLK3_HUMAN (4-246): 3.49e-101: 296: 40.23		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		502706 KLK5_HUMAN (7-247): 3.14e-98: 290: 43.67		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		504752 TMPS5_HUMAN (10-242): 1.72e-95: 288: 35.89		HSP7C_HUMAN (26-637): 0: 916: 66.02
+	Hs
		502554 TMPS5_HUMAN (10-242): 1.72e-95: 288: 35.89		BIP_HUMAN (19-654): 0: 914: 100.00
+	Hs
		871779 TMPS5_HUMAN (10-242): 1.72e-95: 288: 35.89		HSP72_HUMAN (25-636): 0: 905: 64.51