HitPredict

Interactor 1: WEE1 (P07527)
Mitosis inhibitor protein kinase wee1 (EC 2.7.10.2) (P107 protein kinase homolog)
Gene: WEE1

Interactor 2: POF1 (P87053)
F-box/WD repeat-containing protein pof1 (Skp1-binding protein 1)
Gene: POF1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29361524
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 877 Sp			1 605
+	Sc
		431146 FPK1_YEAST (151-853): 9.65e-120: 386: 16.56		CDC4_YEAST (45-560): 1.78e-80: 271: 20.21
+	Mm
		593490 KPCA_MOUSE (407-872): 3.12e-125: 394: 15.78		FBXW7_MOUSE (339-602): 5.75e-76: 257: 32.59
+	Mm
		973813 KPCZ_MOUSE (335-873): 1.53e-123: 387: 16.24		FBXW7_MOUSE (339-602): 5.75e-76: 257: 32.59
+	Hs
		625543 CDK2_HUMAN (563-846): 1.71e-127: 386: 22.64		FBXW7_HUMAN (339-602): 2.33e-75: 255: 32.59
+	Hs
		681967 AKT1_HUMAN (451-871): 1.36e-124: 386: 18.57		FBXW7_HUMAN (339-602): 2.33e-75: 255: 32.59
+	Hs
		415016 CDK1_HUMAN (563-846): 2.87e-123: 376: 21.62		FBXW7_HUMAN (339-602): 2.33e-75: 255: 32.59
+	Hs
		625202 CDK2_HUMAN (563-846): 1.71e-127: 386: 22.64		LIS1_HUMAN (378-595): 2.29e-55: 194: 21.95
+	Hs
		414806 CDK1_HUMAN (563-846): 2.87e-123: 376: 21.62		LIS1_HUMAN (378-595): 2.29e-55: 194: 21.95
+	Hs
		1288348 CDK12_HUMAN (65-853): 5.79e-129: 423: 16.43		SNR40_HUMAN (136-377): 3.04e-32: 129: 13.62
+	Hs
		1346957 CDK12_HUMAN (65-853): 5.79e-129: 423: 16.43		NLE1_HUMAN (76-260): 8.09e-16: 82.2: 10.16
+	Dm
		1213390 AKT1_DROME (317-871): 3.01e-126: 394: 14.39		Q9VDE3_DROME (474-603): 1.45e-24: 109: 19.70
+	Dm
		218248 AKT1_DROME (317-871): 3.01e-126: 394: 14.39		O44382_DROME (474-603): 1.26e-24: 109: 19.70
+	Hs
		682082 AKT1_HUMAN (451-871): 1.36e-124: 386: 18.57		FBW1A_HUMAN (462-603): 2.16e-25: 112: 15.97
+	Hs
		568836 KAPCA_HUMAN (526-873): 5.24e-123: 377: 20.11		FBW1A_HUMAN (462-603): 2.16e-25: 112: 15.97
+	Hs
		415113 CDK1_HUMAN (563-846): 2.87e-123: 376: 21.62		FBW1A_HUMAN (462-603): 2.16e-25: 112: 15.97
+	Hs
		568826 KAPCA_HUMAN (526-873): 5.24e-123: 377: 20.11		FBW1B_HUMAN (462-603): 8.89e-25: 110: 16.67
+	Dm
		1213409 AKT1_DROME (317-871): 3.01e-126: 394: 14.39		NLE_DROME (83-259): 2.18e-16: 84.2: 10.73
+	Hs
		673289 WEE1_HUMAN (547-830): 1.42e-22: 105: 28.85		FBXW7_HUMAN (339-602): 2.33e-75: 255: 32.59
+	Sc
		701875 SWE1_YEAST (491-790): 9.13e-57: 211: 45.66		MET30_YEAST (499-605): 2.92e-18: 90.7: 14.82
+	Hs
		673304 WEE1_HUMAN (547-830): 1.42e-22: 105: 28.85		FBW1B_HUMAN (462-603): 8.89e-25: 110: 16.67