Interactor 1: ADRB2 (P07550)
Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)
Gene: ADRB2

Interactor 2: DRD4 (P21917)
D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor)
Gene: DRD4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 22759790
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~7tm_1
Common GO terms GO:0005886 - plasma membrane
GO:0015459 - potassium channel regulator activity
GO:0016020 - membrane
GO:0051380 - norepinephrine binding
GO:0071880 - adenylate cyclase-activating adrenergic receptor signaling pathway
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 413
Hs

1 419
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024