HitPredict

Interactor 1: ADRB2 (P07550)
Beta-2 adrenergic receptor (Beta-2 adrenoreceptor) (Beta-2 adrenoceptor)
Gene: ADRB2

Interactor 2: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.834

Property	Details
Experiments	28388416, 15782186, 23798571
Identification Methods	proximity labelling technology, fluorescent resonance energy transfer, affinity chromatography technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	7tm_1~WD40
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0044877 - protein-containing complex binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 413 Hs			1 340
+	Hs
		429007 ADRB2_HUMAN (1-413): 1.07e-122: 363: 100.00		GBB2_HUMAN (1-340): 1e-105: 314: 90.29
+	Hs
		429130 ADRB2_HUMAN (1-413): 1.07e-122: 363: 100.00		GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88
+	Rn
		495780 ADRB2_RAT (1-413): 1.35e-117: 350: 87.32		GNB5_RAT (129-340): 1.48e-45: 160: 21.92
+	Hs
		445805 ADA2A_HUMAN (3-229): 5.19e-38: 144: 36.36		GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00
+	Hs
		658220 5HT2C_HUMAN (53-340): 2.84e-36: 139: 32.81		GBB2_HUMAN (1-340): 1e-105: 314: 90.29