Interactor 1: RPAC1 (P07703)
DNA-directed RNA polymerases I and III subunit RPAC1 (RNA polymerases I and III subunit AC1) (C37) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (AC40) (C40)
Gene: RPC40

Interactor 2: RPA2 (P22138)
DNA-directed RNA polymerase I subunit RPA135 (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (A135) (DNA-directed RNA polymerase I polypeptide 2) (RNA polymerase I subunit 2)
Gene: RPA135

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 10393904, 11805826, 11805837, 16554755, 16429126, 37968396, 22940862, 23209026, 14759368
Identification Methods two hybrid, tandem affinity purification, anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_L~RNA_pol_Rpb2_6
Common GO terms GO:0001054 - RNA polymerase I activity
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005736 - RNA polymerase I complex
GO:0006360 - transcription by RNA polymerase I
and 5 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 335
Sc

1 1203
+ Sc
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Sc
+ Hs
+ Dm
+ Hs
+ Sc
+ Sp
+ Sc
+ Pf
+ Hv
+ Hv

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024