HitPredict

Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: MARCS (P29966)
Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL)
Gene: MARCKS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005925 - focal adhesion GO:0005938 - cell cortex GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 332
+	Hs
		166025 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		SYNJ2_HUMAN (63-316): 5.31e-21: 96: 9.20
+	Hs
		203199 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		SYNJ1_HUMAN (8-329): 5.64e-12: 69.1: 9.41
+	Mm
		923936 PROF1_MOUSE (1-140): 5.37e-77: 226: 95.71		PCLO_MOUSE (1-315): 3.36e-09: 60.6: 13.02
+	Hs
		430285 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		TITIN_HUMAN (1-308): 6.95e-09: 59.4: 10.71
+	Mm
		1337493 PROF2_MOUSE (1-140): 9.83e-75: 220: 61.43		PCLO_MOUSE (1-315): 3.36e-09: 60.6: 13.02