HitPredict

Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28007913
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 870
+	Hs
		430383 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		MACF1_HUMAN (505-867): 1.44e-74: 269: 13.79
+	Hs
		430229 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		DNMBP_HUMAN (7-559): 6.75e-29: 126: 15.27
+	Hs
		203199 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		SYNJ1_HUMAN (281-696): 4.9e-10: 65.7: 13.47
+	Mm
		923936 PROF1_MOUSE (1-140): 5.37e-77: 226: 95.71		PCLO_MOUSE (15-743): 1.43e-09: 64.5: 10.52
+	Hs
		430285 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		TITIN_HUMAN (56-404): 7.26e-09: 62.1: 14.93
+	Mm
		1337493 PROF2_MOUSE (1-140): 9.83e-75: 220: 61.43		PCLO_MOUSE (15-743): 1.43e-09: 64.5: 10.52