Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.898

The method score is based on:

Property Details
Experiments 10411937, 35271311, 19338310, 19000816
Identification Methods pull down, affinity chromatography technology, two hybrid, cosedimentation in solution, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Profilin
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005925 - focal adhesion
and 5 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 140
Hs

1 375
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024