HitPredict

Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0030036 - actin cytoskeleton organization GO:0070062 - extracellular exosome GO:0098978 - glutamatergic synapse
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 192
+	Hs
		545227 PROF2_HUMAN (1-140): 1.13e-74: 220: 61.43		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		430119 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		430009 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79
+	Hs
		430044 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49