HitPredict

Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: MAP1A (P78559)
Microtubule-associated protein 1A (MAP-1A) (Proliferation-related protein p80) [Cleaved into: MAP1A heavy chain; MAP1 light chain LC2]
Gene: MAP1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 2803
+	Hs
		430023 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		TPR_HUMAN (401-2740): 1.55e-57: 224: 8.84
+	Hs
		430194 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		ITSN1_HUMAN (1332-1930): 3.27e-43: 177: 13.88
+	Mm
		923936 PROF1_MOUSE (1-140): 5.37e-77: 226: 95.71		PCLO_MOUSE (1658-2682): 5.88e-29: 130: 9.66
+	Mm
		1337493 PROF2_MOUSE (1-140): 9.83e-75: 220: 61.43		PCLO_MOUSE (1658-2682): 5.88e-29: 130: 9.66
+	Hs
		430285 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		TITIN_HUMAN (139-1866): 7.45e-22: 107: 10.64