HitPredict

Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:0016020 - membrane GO:0030036 - actin cytoskeleton organization GO:0045296 - cadherin binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 2472
+	Hs
		430138 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52
+	Hs
		430182 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		GOGB1_HUMAN (2-1186): 3.65e-38: 160: 10.57
+	Hs
		714965 PROF2_HUMAN (1-140): 1.13e-74: 220: 61.43		GOGB1_HUMAN (2-1186): 3.65e-38: 160: 10.57
+	Hs
		430383 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		MACF1_HUMAN (9-1261): 9.1e-18: 93.6: 12.48