HitPredict

Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: AFF4 (Q9UHB7)
AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31 protein) (Protein AF-5q31) (Major CDK9 elongation factor-associated protein)
Gene: AFF4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	33596420
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 1163
+	Hs
		430150 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		ZO1_HUMAN (80-902): 3.89e-34: 145: 12.83
+	Hs
		430167 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		MYO9B_HUMAN (494-931): 5.09e-27: 121: 13.15
+	Mm
		923936 PROF1_MOUSE (1-140): 5.37e-77: 226: 95.71		PCLO_MOUSE (7-987): 3.87e-21: 102: 8.11
+	Mm
		1337493 PROF2_MOUSE (1-140): 9.83e-75: 220: 61.43		PCLO_MOUSE (7-987): 3.87e-21: 102: 8.11
+	Hs
		430141 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		ANK2_HUMAN (263-904): 2.21e-13: 77.4: 13.44