HitPredict

Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	28024152
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001843 - neural tube closure GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005938 - cell cortex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 522
+	Hs
		715021 PROF2_HUMAN (1-140): 1.13e-74: 220: 61.43		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		430179 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		301552 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		301642 PROF2_HUMAN (1-140): 1.13e-74: 220: 61.43		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		714997 PROF2_HUMAN (1-140): 1.13e-74: 220: 61.43		TRI31_HUMAN (58-334): 3.02e-35: 138: 15.00