HitPredict

Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: FHOD1 (Q9Y613)
FH1/FH2 domain-containing protein 1 (Formin homolog overexpressed in spleen 1) (FHOS) (Formin homology 2 domain-containing protein 1)
Gene: FHOD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0016020 - membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 1164
+	Hs
		715022 PROF2_HUMAN (1-140): 1.13e-74: 220: 61.43		FHOD1_HUMAN (1-1164): 0: 1128: 100.00
+	Hs
		237549 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		DIAP1_HUMAN (259-1122): 8.21e-125: 416: 16.20
+	Hs
		237564 PROF2_HUMAN (1-140): 1.13e-74: 220: 61.43		DIAP1_HUMAN (259-1122): 8.21e-125: 416: 16.20
+	Hs
		430352 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		DIAP3_HUMAN (558-1132): 3.26e-114: 385: 15.91
+	Hs
		243087 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		DIAP2_HUMAN (586-1083): 3.32e-114: 383: 17.98
+	Hs
		314830 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		FMNL1_HUMAN (592-1081): 4.72e-109: 369: 18.27
+	Hs
		430307 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		FMNL2_HUMAN (599-1072): 6.62e-107: 363: 16.57
+	Hs
		314847 PROF2_HUMAN (1-140): 1.13e-74: 220: 61.43		FMNL1_HUMAN (592-1081): 4.72e-109: 369: 18.27
+	Hs
		430197 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		INF2_HUMAN (143-1133): 2.19e-104: 359: 15.95
+	Hs
		714970 PROF2_HUMAN (1-140): 1.13e-74: 220: 61.43		INF2_HUMAN (143-1133): 2.19e-104: 359: 15.95
+	Hs
		430356 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		FMN2_HUMAN (573-1023): 1.6e-98: 347: 20.21