HitPredict - High confidence protein-protein interactions

Interactor 1: CD3E (P07766)
T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain) (CD antigen CD3e)
Gene: CD3E

Interactor 2: CD3G (P09693)
T-cell surface glycoprotein CD3 gamma chain (T-cell receptor T3 gamma chain) (CD antigen CD3g)
Gene: CD3G

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	9582308, 20890284
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ig_4~Ig_5
Common GO terms	GO:0002250 - adaptive immune response GO:0004888 - transmembrane signaling receptor activity GO:0005886 - plasma membrane GO:0007166 - cell surface receptor signaling pathway GO:0009897 - external side of plasma membrane and 10 others more... GO:0030159 - signaling receptor complex adaptor activity GO:0042105 - alpha-beta T cell receptor complex GO:0042106 - gamma-delta T cell receptor complex GO:0042110 - T cell activation GO:0042608 - T cell receptor binding GO:0045059 - positive thymic T cell selection GO:0046629 - gamma-delta T cell activation GO:0046631 - alpha-beta T cell activation GO:0050852 - T cell receptor signaling pathway GO:0065003 - protein-containing complex assembly
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	207
Hs

1	182

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Last updated: 15 Jul 2024