Interactor 1: CD3E (P07766)
T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain) (CD antigen CD3e)
Gene: CD3E

Interactor 2: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.684

The method score is based on:

Property Details
Experiments 17617578, 12110186, 18955169
Identification Methods affinity chromatography technology, unspecified method, pull down, filamentous phage display, peptide array, anti tag coimmunoprecipitation, nuclear magnetic resonance, enzyme linked immunosorbent assay
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0007172 - signal complex assembly
GO:0030159 - signaling receptor complex adaptor activity
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 207
Hs

1 377
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024