HitPredict

Interactor 1: CD3E (P07766)
T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain) (CD antigen CD3e)
Gene: CD3E

Interactor 2: SHC1 (P29353)
SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	11855827
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 207 Hs			1 583
+	Hs
		208975 CD3E_HUMAN (1-207): 5.3e-142: 395: 100.00		NCK2_HUMAN (363-579): 5.31e-45: 165: 18.83
+	Hs
		430679 CD3E_HUMAN (1-207): 5.3e-142: 395: 100.00		NCK1_HUMAN (360-575): 1.55e-41: 155: 18.30
+	Hs
		430683 CD3E_HUMAN (1-207): 5.3e-142: 395: 100.00		P85A_HUMAN (300-581): 2.38e-38: 152: 15.31
+	Hs
		129167 CD3E_HUMAN (1-207): 5.3e-142: 395: 100.00		P85B_HUMAN (358-581): 2.69e-29: 125: 17.47
+	Mm
		610139 CD3E_MOUSE (1-207): 5.02e-110: 314: 59.42		VAV_MOUSE (163-579): 6.29e-54: 198: 11.54