HitPredict

Interactor 1: SYEP (P07814)
Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) (Cell proliferation-inducing gene 32 protein) (Glutamatyl-prolyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase)]
Gene: EPRS1

Interactor 2: HSC20 (Q8IWL3)
Iron-sulfur cluster co-chaperone protein HscB (DnaJ homolog subfamily C member 20) [Cleaved into: Iron-sulfur cluster co-chaperone protein HscB, cytoplasmic (C-HSC20); Iron-sulfur cluster co-chaperone protein HscB, mitochondrial]
Gene: HSCB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.625

Property	Details
Experiments	28380382, 24606901
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1512 Hs			1 235
+	Hs
		58237 SYTC2_HUMAN (707-1411): 3.75e-171: 535: 14.66		HSC20_HUMAN (1-235): 1.7e-133: 376: 100.00
+	Hs
		1218962 SYTM_HUMAN (774-1411): 7.77e-150: 476: 14.87		HSC20_HUMAN (1-235): 1.7e-133: 376: 100.00
+	Hs
		1126905 SYEM_HUMAN (198-487): 4.99e-64: 229: 21.75		HSC20_HUMAN (1-235): 1.7e-133: 376: 100.00