Interactor 1: SYEP (P07814)
Bifunctional glutamate/proline--tRNA ligase (Bifunctional aminoacyl-tRNA synthetase) (Cell proliferation-inducing gene 32 protein) (Glutamatyl-prolyl-tRNA synthetase) [Includes: Glutamate--tRNA ligase (EC 6.1.1.17) (Glutamyl-tRNA synthetase) (GluRS); Proline--tRNA ligase (EC 6.1.1.15) (Prolyl-tRNA synthetase)]
Gene: EPRS1

Interactor 2: SYLC (Q9P2J5)
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS) (cLRS)
Gene: LARS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.694

The method score is based on:

Property Details
Experiments 36347866, 28514442, 27684187, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006418 - tRNA aminoacylation for protein translation
GO:0017101 - aminoacyl-tRNA synthetase multienzyme complex
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1512
Hs

1 1176
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Dm
+ Hs
+ Sc
+ Sc
+ Dm
+ Hs
+ Mt
+ Tk
+ Sc
+ Sc

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Last updated: 15 Jul 2024