HitPredict

Interactor 1: CATB (P07858)
Cathepsin B (EC 3.4.22.1) (APP secretase) (APPS) (Cathepsin B1) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain]
Gene: CTSB

Interactor 2: CATB (P07858)
Cathepsin B (EC 3.4.22.1) (APP secretase) (APPS) (Cathepsin B1) [Cleaved into: Cathepsin B light chain; Cathepsin B heavy chain]
Gene: CTSB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 34709727
Identification Methods affinity chromatography technology, proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_C1~Peptidase_C1, Peptidase_C1~Propeptide_C1
Common GO terms GO:0004197 - cysteine-type endopeptidase activity
GO:0005518 - collagen binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005764 - lysosome
and 21 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 339
Hs

1 339
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024