HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: EPHA1 (P21709)
Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)
Gene: EPHA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22939624
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 732 Hs			1 976
+	Hs
		431692 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPHA4_HUMAN (5-975): 0: 1108: 43.50
+	Hs
		431691 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPHB1_HUMAN (26-975): 0: 1105: 42.11
+	Hs
		431562 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPHA3_HUMAN (22-975): 0: 1097: 43.01
+	Hs
		438028 HS90B_HUMAN (19-732): 0: 1059: 86.13		EPHB1_HUMAN (26-975): 0: 1105: 42.11
+	Hs
		437892 HS90B_HUMAN (19-732): 0: 1059: 86.13		EPHA1_HUMAN (1-976): 0: 1103: 100.00
+	Hs
		431561 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPHA2_HUMAN (24-976): 0: 1056: 49.90
+	Hs
		437918 HS90B_HUMAN (19-732): 0: 1059: 86.13		EPHA2_HUMAN (24-976): 0: 1056: 49.90
+	Hs
		171280 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPHB6_HUMAN (11-971): 0: 907: 36.44
+	Hs
		171281 HS90B_HUMAN (19-732): 0: 1059: 86.13		EPHB6_HUMAN (11-971): 0: 907: 36.44
+	Hs
		431568 HS90A_HUMAN (1-732): 0: 1087: 100.00		UFO_HUMAN (274-964): 2.03e-146: 459: 23.29
+	Hs
		431770 HS90A_HUMAN (1-732): 0: 1087: 100.00		TYRO3_HUMAN (276-964): 4.07e-145: 456: 23.98
+	Hs
		431488 HS90A_HUMAN (1-732): 0: 1087: 100.00		INSRR_HUMAN (291-924): 9.51e-139: 449: 24.70
+	Hs
		431438 HS90A_HUMAN (1-732): 0: 1087: 100.00		IGF1R_HUMAN (269-885): 5.75e-137: 446: 21.38
+	Hs
		431788 HS90A_HUMAN (1-732): 0: 1087: 100.00		MERTK_HUMAN (274-909): 3.08e-140: 446: 24.71
+	Hs
		437923 HS90B_HUMAN (19-732): 0: 1059: 86.13		UFO_HUMAN (274-964): 2.03e-146: 459: 23.29
+	Hs
		437855 HS90B_HUMAN (19-732): 0: 1059: 86.13		INSRR_HUMAN (291-924): 9.51e-139: 449: 24.70
+	Hs
		435497 HS90B_HUMAN (19-732): 0: 1059: 86.13		IGF1R_HUMAN (269-885): 5.75e-137: 446: 21.38
+	Hs
		431765 HS90A_HUMAN (1-732): 0: 1087: 100.00		FAK1_HUMAN (630-884): 1.18e-63: 236: 45.88
+	Hs
		431507 HS90A_HUMAN (1-732): 0: 1087: 100.00		FER_HUMAN (620-880): 2.96e-64: 234: 44.40
+	Hs
		437867 HS90B_HUMAN (19-732): 0: 1059: 86.13		FER_HUMAN (620-880): 2.96e-64: 234: 44.40