HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: ZAP70 (P43403)
Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)
Gene: ZAP70

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16888650
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 732 Hs			1 619
+	Hs
		411551 HS90A_HUMAN (1-732): 0: 1087: 100.00		LCK_HUMAN (58-608): 4.13e-159: 467: 26.79
+	Hs
		431561 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPHA2_HUMAN (20-614): 3.34e-152: 465: 22.71
+	Hs
		431626 HS90A_HUMAN (1-732): 0: 1087: 100.00		ABL2_HUMAN (120-617): 2.51e-147: 457: 29.14
+	Hs
		431691 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPHB1_HUMAN (70-616): 1.27e-147: 453: 25.49
+	Hs
		431481 HS90A_HUMAN (1-732): 0: 1087: 100.00		SRC_HUMAN (73-607): 2.65e-149: 443: 25.14
+	Hs
		411945 HS90A_HUMAN (1-732): 0: 1087: 100.00		FYN_HUMAN (62-607): 2.84e-147: 438: 24.87
+	Hs
		431562 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPHA3_HUMAN (67-615): 1.19e-141: 437: 23.99
+	Hs
		431692 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPHA4_HUMAN (72-616): 4.07e-141: 436: 24.65
+	Hs
		431666 HS90A_HUMAN (1-732): 0: 1087: 100.00		BLK_HUMAN (77-608): 1.4e-146: 435: 26.11
+	Hs
		431451 HS90A_HUMAN (1-732): 0: 1087: 100.00		FGR_HUMAN (109-610): 1.35e-144: 431: 25.05
+	Hs
		431445 HS90A_HUMAN (1-732): 0: 1087: 100.00		HCK_HUMAN (43-608): 6.8e-143: 426: 23.69
+	Hs
		337312 HS90A_HUMAN (1-732): 0: 1087: 100.00		ABL1_HUMAN (90-601): 9.22e-135: 423: 26.31
+	Hs
		431433 HS90A_HUMAN (1-732): 0: 1087: 100.00		YES_HUMAN (111-607): 1.3e-140: 421: 24.35
+	Hs
		431627 HS90A_HUMAN (1-732): 0: 1087: 100.00		FRK_HUMAN (80-604): 9.15e-140: 418: 24.72
+	Hs
		431619 HS90A_HUMAN (1-732): 0: 1087: 100.00		CSK_HUMAN (90-599): 3.17e-140: 417: 27.41
+	Hs
		431782 HS90A_HUMAN (1-732): 0: 1087: 100.00		ITK_HUMAN (110-599): 4.17e-137: 415: 26.35
+	Hs
		431673 HS90A_HUMAN (1-732): 0: 1087: 100.00		BMX_HUMAN (147-599): 1.3e-135: 413: 26.74
+	Hs
		431434 HS90A_HUMAN (1-732): 0: 1087: 100.00		LYN_HUMAN (75-608): 2.44e-137: 412: 24.72
+	Hs
		431838 HS90A_HUMAN (1-732): 0: 1087: 100.00		PTK6_HUMAN (129-596): 3.44e-136: 406: 27.94
+	Hs
		431765 HS90A_HUMAN (1-732): 0: 1087: 100.00		FAK1_HUMAN (344-593): 1.41e-59: 217: 43.03