HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: TP4A2 (Q12974)
Protein tyrosine phosphatase type IVA 2 (EC 3.1.3.48) (HU-PP-1) (OV-1) (PTP(CAAXII)) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2)
Gene: PTP4A2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	36300783
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 167
+	Hs
		438119 HS90B_HUMAN (19-732): 0: 1059: 86.13		TP4A2_HUMAN (1-167): 6.88e-68: 205: 100.00
+	Hs
		431707 HS90A_HUMAN (1-732): 0: 1087: 100.00		PTEN_HUMAN (2-158): 1.56e-47: 160: 19.67
+	Mm
		139300 HS90A_MOUSE (1-732): 0: 1083: 97.82		PTEN_MOUSE (2-158): 1.51e-47: 160: 19.67
+	Mm
		139308 HS90B_MOUSE (19-732): 0: 1063: 86.98		PTEN_MOUSE (2-158): 1.51e-47: 160: 19.67
+	Hs
		438038 HS90B_HUMAN (19-732): 0: 1059: 86.13		PTEN_HUMAN (2-158): 1.56e-47: 160: 19.67
+	Mm
		139302 ENPL_MOUSE (14-732): 0: 901: 45.07		PTEN_MOUSE (2-158): 1.51e-47: 160: 19.67
+	Hs
		538178 ENPL_HUMAN (14-701): 0: 898: 46.78		PTEN_HUMAN (2-158): 1.56e-47: 160: 19.67
+	Sc
		366737 HSP82_YEAST (16-732): 0: 907: 60.08		CDC14_YEAST (11-147): 4.2e-38: 138: 30.44