HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: DRB5 (Q30154)
HLA class II histocompatibility antigen, DR beta 5 chain (DR beta-5) (DR2-beta-2) (Dw2) (MHC class II antigen DRB5)
Gene: HLA-DRB5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20458337
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0023026 - MHC class II protein complex binding GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 266
+	Hs
		431484 HS90A_HUMAN (1-732): 0: 1087: 100.00		DRB4_HUMAN (1-266): 2.79e-100: 295: 86.09
+	Hs
		431734 HS90A_HUMAN (1-732): 0: 1087: 100.00		DRB3_HUMAN (1-266): 5.8e-100: 294: 86.84
+	Hs
		438223 HS90B_HUMAN (19-732): 0: 1059: 86.13		DRB5_HUMAN (1-266): 3.49e-103: 302: 100.00
+	Hs
		437851 HS90B_HUMAN (19-732): 0: 1059: 86.13		DRB4_HUMAN (1-266): 2.79e-100: 295: 86.09
+	Hs
		438072 HS90B_HUMAN (19-732): 0: 1059: 86.13		DRB3_HUMAN (1-266): 5.8e-100: 294: 86.84
+	Hs
		354659 HS90A_HUMAN (1-732): 0: 1087: 100.00		DRA_HUMAN (117-223): 3.31e-11: 63.5: 30.84
+	Hs
		354661 HS90B_HUMAN (19-732): 0: 1059: 86.13		DRA_HUMAN (117-223): 3.31e-11: 63.5: 30.84