HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: LMTK1 (Q6ZMQ8)
Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP)
Gene: AATK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0016020 - membrane GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 732 Hs			1 1374
+	Hs
		431776 HS90A_HUMAN (1-732): 0: 1087: 100.00		ACK1_HUMAN (54-854): 2.25e-146: 474: 21.51
+	Hs
		431691 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPHB1_HUMAN (6-505): 2.12e-123: 410: 19.80
+	Hs
		431536 HS90A_HUMAN (1-732): 0: 1087: 100.00		FGFR3_HUMAN (29-448): 5.82e-123: 403: 23.42
+	Hs
		169159 HS90A_HUMAN (1-732): 0: 1087: 100.00		MUSK_HUMAN (7-402): 6.06e-121: 400: 25.42
+	Hs
		431472 HS90A_HUMAN (1-732): 0: 1087: 100.00		FGFR1_HUMAN (28-460): 6.26e-120: 396: 21.00
+	Hs
		169160 HS90B_HUMAN (19-732): 0: 1059: 86.13		MUSK_HUMAN (7-402): 6.06e-121: 400: 25.42
+	Hs
		431892 HS90A_HUMAN (1-732): 0: 1087: 100.00		NTRK3_HUMAN (24-398): 5.5e-110: 369: 25.54
+	Hs
		431562 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPHA3_HUMAN (12-404): 1.11e-104: 358: 23.74
+	Hs
		431901 HS90A_HUMAN (1-732): 0: 1087: 100.00		NTRK2_HUMAN (30-400): 4.89e-106: 357: 27.78
+	Hs
		411551 HS90A_HUMAN (1-732): 0: 1087: 100.00		LCK_HUMAN (98-410): 1.51e-107: 352: 24.20
+	Hs
		431434 HS90A_HUMAN (1-732): 0: 1087: 100.00		LYN_HUMAN (109-410): 9.62e-106: 347: 24.75
+	Rn
		948934 HS90A_RAT (1-732): 0: 1085: 97.95		LYN_RAT (109-410): 5.81e-106: 347: 25.08
+	Hs
		411945 HS90A_HUMAN (1-732): 0: 1087: 100.00		FYN_HUMAN (104-408): 1.36e-104: 344: 30.07
+	Hs
		431438 HS90A_HUMAN (1-732): 0: 1087: 100.00		IGF1R_HUMAN (119-391): 2.65e-38: 159: 34.51
+	Hs
		431907 HS90A_HUMAN (1-732): 0: 1087: 100.00		DDR2_HUMAN (108-395): 1.06e-36: 152: 33.86
+	Hs
		431488 HS90A_HUMAN (1-732): 0: 1087: 100.00		INSRR_HUMAN (119-425): 6.94e-34: 144: 33.43
+	Hs
		384111 HS90A_HUMAN (1-732): 0: 1087: 100.00		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		432361 HS90A_HUMAN (1-732): 0: 1087: 100.00		ALK_HUMAN (109-386): 2.69e-32: 139: 32.99
+	Hs
		431673 HS90A_HUMAN (1-732): 0: 1087: 100.00		BMX_HUMAN (119-391): 1.16e-32: 138: 32.12
+	Hs
		337312 HS90A_HUMAN (1-732): 0: 1087: 100.00		ABL1_HUMAN (588-1118): 4.91e-10: 66.4: 13.32