HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: CD37L (Q7L3B6)
Hsp90 co-chaperone Cdc37-like 1 (Hsp90-associating relative of Cdc37)
Gene: CDC37L1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.919

The method score is based on:

Property Details
Experiments 26496610, 11413142, 33961781, 19875381, 25036637
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC37_M~HSP90
Common GO terms GO:0005576 - extracellular region
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006457 - protein folding
GO:0050821 - protein stabilization
and 1 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 732
Hs

1 337
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Dm
+ Ce
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024