HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: RNF31 (Q96EP0)
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) (Zinc in-between-RING-finger ubiquitin-associated domain protein)
Gene: RNF31

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27545878
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 1072
+	Hs
		438429 HS90B_HUMAN (19-732): 0: 1059: 86.13		RNF31_HUMAN (1-1072): 0: 1111: 100.00
+	Hs
		431979 HS90A_HUMAN (1-732): 0: 1087: 100.00		RN19B_HUMAN (698-946): 5.65e-42: 167: 22.43
+	Hs
		438287 HS90B_HUMAN (19-732): 0: 1059: 86.13		RN19B_HUMAN (698-946): 5.65e-42: 167: 22.43
+	Hs
		432330 HS90A_HUMAN (1-732): 0: 1087: 100.00		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44
+	Hs
		438588 HS90B_HUMAN (19-732): 0: 1059: 86.13		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44
+	Hs
		538157 ENPL_HUMAN (14-701): 0: 898: 46.78		R144A_HUMAN (695-926): 5.41e-59: 206: 20.33
+	Hs
		538438 ENPL_HUMAN (14-701): 0: 898: 46.78		ZRAN1_HUMAN (226-379): 5.88e-20: 97.7: 19.44