HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: RHBT2 (Q9BYZ6)
Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein) (p83)
Gene: RHOBTB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.620

Property	Details
Experiments	26517842, 24608665
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005525 - GTP binding GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 727
+	Hs
		438497 HS90B_HUMAN (19-732): 0: 1059: 86.13		RHBT2_HUMAN (1-705): 9.08e-177: 524: 100.00
+	Hs
		297569 HS90A_HUMAN (1-732): 0: 1087: 100.00		RHBT1_HUMAN (1-708): 6.34e-160: 480: 67.65
+	Hs
		297572 HS90B_HUMAN (19-732): 0: 1059: 86.13		RHBT1_HUMAN (1-708): 6.34e-160: 480: 67.65
+	Hs
		301170 HS90A_HUMAN (1-732): 0: 1087: 100.00		RHBT3_HUMAN (82-686): 4.81e-87: 287: 20.52
+	Hs
		214040 HS90A_HUMAN (1-732): 0: 1087: 100.00		SPOP_HUMAN (305-670): 2.13e-72: 241: 13.30
+	Mm
		432417 HS90A_MOUSE (1-732): 0: 1083: 97.82		RAB1A_MOUSE (1-236): 1.37e-70: 230: 16.87
+	Mm
		513667 HS90B_MOUSE (19-732): 0: 1063: 86.98		RAB1A_MOUSE (1-236): 1.37e-70: 230: 16.87
+	Sc
		350829 HSP82_YEAST (16-732): 0: 907: 60.08		YPT1_YEAST (1-228): 3.63e-69: 227: 18.18
+	Sc
		350841 HSC82_YEAST (16-732): 0: 902: 59.39		YPT1_YEAST (1-228): 3.63e-69: 227: 18.18
+	Zm
		35501 A0A1D6LMW9_MAIZE (4-704): 0: 843: 46.30		B4FNE3_MAIZE (15-208): 1.72e-85: 269: 38.07