HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: BTBD1 (Q9H0C5)
BTB/POZ domain-containing protein 1 (Hepatitis C virus NS5A-transactivated protein 8) (HCV NS5A-transactivated protein 8)
Gene: BTBD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.534

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid, luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 482
+	Hs
		432290 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLHL1_HUMAN (5-480): 2.99e-113: 352: 17.10
+	Hs
		432115 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLHL6_HUMAN (4-480): 6.65e-109: 337: 16.21
+	Hs
		438555 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLHL1_HUMAN (5-480): 2.99e-113: 352: 17.10
+	Hs
		438402 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLHL6_HUMAN (4-480): 6.65e-109: 337: 16.21
+	Hs
		431925 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLH26_HUMAN (43-340): 2.93e-81: 265: 23.03
+	Hs
		432143 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLH29_HUMAN (9-339): 2.68e-78: 263: 17.82
+	Hs
		431957 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLH10_HUMAN (57-299): 8.67e-77: 253: 21.55
+	Hs
		438236 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLH26_HUMAN (43-340): 2.93e-81: 265: 23.03
+	Hs
		438426 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLH29_HUMAN (9-339): 2.68e-78: 263: 17.82
+	Hs
		438266 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLH10_HUMAN (57-299): 8.67e-77: 253: 21.55
+	Hs
		431841 HS90A_HUMAN (1-732): 0: 1087: 100.00		KEAP1_HUMAN (325-470): 3.91e-20: 95.6: 13.46
+	Hs
		432109 HS90A_HUMAN (1-732): 0: 1087: 100.00		KBTB7_HUMAN (50-255): 3.91e-12: 70.5: 28.04
+	Hs
		432323 HS90A_HUMAN (1-732): 0: 1087: 100.00		KLH13_HUMAN (335-458): 2e-11: 68.3: 7.26
+	Hs
		438163 HS90B_HUMAN (19-732): 0: 1059: 86.13		KEAP1_HUMAN (325-470): 3.91e-20: 95.6: 13.46
+	Hs
		438396 HS90B_HUMAN (19-732): 0: 1059: 86.13		KBTB7_HUMAN (50-255): 3.91e-12: 70.5: 28.04
+	Hs
		438582 HS90B_HUMAN (19-732): 0: 1059: 86.13		KLH13_HUMAN (335-458): 2e-11: 68.3: 7.26