HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: TAB2 (Q9NYJ8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
Gene: TAB2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	19875381, 14743216
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 693
+	Hs
		431504 HS90A_HUMAN (1-732): 0: 1087: 100.00		MUC1_HUMAN (23-434): 8.02e-18: 90.2: 8.89
+	Hs
		438364 HS90B_HUMAN (19-732): 0: 1059: 86.13		KMT2C_HUMAN (103-538): 1.38e-09: 63.9: 14.25
+	Dm
		365428 HSP83_DROME (15-732): 0: 1034: 78.41		RPB1_DROME (131-425): 5.47e-11: 68.5: 15.27
+	Sc
		366285 HSP82_YEAST (16-732): 0: 907: 60.08		SEC31_YEAST (37-369): 1.01e-09: 64.3: 11.64
+	Sc
		543728 HSC82_YEAST (16-732): 0: 902: 59.39		SEC31_YEAST (37-369): 1.01e-09: 64.3: 11.64
+	Hs
		538160 ENPL_HUMAN (14-701): 0: 898: 46.78		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81