HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: FKBPL (Q9UIM3)
FK506-binding protein-like (WAF-1/CIP1 stabilizing protein 39) (WISp39)
Gene: FKBPL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	15664193, 23912458, 25036637
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 732 Hs			1 349
+	Hs
		111943 K9JA46_HUMAN (1-732): 0: 1087: 100.00		FKBPL_HUMAN (1-349): 1.14e-87: 269: 100.00
+	Hs
		111936 K9JA46_HUMAN (1-732): 0: 1087: 100.00		FKBP4_HUMAN (83-348): 7.15e-59: 198: 26.30
+	Hs
		431755 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBP4_HUMAN (83-348): 7.15e-59: 198: 26.30
+	Mm
		432409 HS90A_MOUSE (1-732): 0: 1083: 97.82		FKBP4_MOUSE (83-348): 4.54e-60: 201: 26.30
+	Hs
		111937 K9JA46_HUMAN (1-732): 0: 1087: 100.00		FKBP5_HUMAN (83-348): 5.51e-57: 193: 23.53
+	Hs
		431818 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBP5_HUMAN (83-348): 5.51e-57: 193: 23.53
+	Hs
		431781 HS90A_HUMAN (1-732): 0: 1087: 100.00		PPID_HUMAN (78-349): 1.59e-50: 174: 21.45
+	Hs
		213451 HS90A_HUMAN (1-732): 0: 1087: 100.00		SGTA_HUMAN (151-335): 1.67e-45: 159: 23.71
+	Hs
		431850 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBP8_HUMAN (96-349): 1.94e-41: 151: 24.37
+	Hs
		111930 K9JA46_HUMAN (1-732): 0: 1087: 100.00		FKBP6_HUMAN (73-349): 1.03e-41: 150: 21.22
+	Hs
		259914 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBP6_HUMAN (73-349): 1.03e-41: 150: 21.22
+	Hs
		432258 HS90A_HUMAN (1-732): 0: 1087: 100.00		UN45A_HUMAN (208-348): 2.18e-36: 141: 33.33
+	Hs
		213454 HS90B_HUMAN (19-732): 0: 1059: 86.13		SGTA_HUMAN (151-335): 1.67e-45: 159: 23.71
+	Hs
		259915 HS90B_HUMAN (19-732): 0: 1059: 86.13		FKBP6_HUMAN (73-349): 1.03e-41: 150: 21.22
+	Hs
		432268 HS90A_HUMAN (1-732): 0: 1087: 100.00		RPAP3_HUMAN (206-337): 2.43e-27: 114: 26.52
+	Hs
		431886 HS90A_HUMAN (1-732): 0: 1087: 100.00		TOM34_HUMAN (207-333): 6.68e-25: 104: 28.35
+	Hs
		111934 K9JA46_HUMAN (1-732): 0: 1087: 100.00		STIP1_HUMAN (207-337): 8.63e-21: 95.3: 20.61
+	Hs
		431574 HS90A_HUMAN (1-732): 0: 1087: 100.00		STIP1_HUMAN (207-337): 8.63e-21: 95.3: 20.61
+	Hs
		431774 HS90A_HUMAN (1-732): 0: 1087: 100.00		SPAG1_HUMAN (203-340): 3.25e-20: 94: 29.71
+	Hs
		437930 HS90B_HUMAN (19-732): 0: 1059: 86.13		STIP1_HUMAN (207-337): 8.63e-21: 95.3: 20.61