HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.770

The method score is based on:

Property Details
Experiments 16275660, 27353360, 23999428, 30911017, 32600329, 33571422, 36279628, 16307917, 17317785, 21454478, 18818696, 22824801, 15001357, 20661446, 19875381, 21360678, 26330542, 35148989, 17324930, 15538384 and 15 others

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Identification Methods unspecified method, affinity chromatography technology, biochemical, x-ray crystallography, pull down, enzymatic study, two hybrid, anti tag coimmunoprecipitation, filter binding, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
and 7 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 732
Hs

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Last updated: 15 Jul 2024