HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: HIF3A (Q9Y2N7)
Hypoxia-inducible factor 3-alpha (HIF-3-alpha) (HIF3-alpha) (Basic-helix-loop-helix-PAS protein MOP7) (Class E basic helix-loop-helix protein 17) (bHLHe17) (HIF3-alpha-1) (Inhibitory PAS domain protein) (IPAS) (Member of PAS protein 7) (PAS domain-containing protein 7)
Gene: HIF3A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15319539
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 669
+	Hs
		431844 HS90A_HUMAN (1-732): 0: 1087: 100.00		SIM2_HUMAN (16-666): 1.85e-151: 455: 26.46
+	Hs
		431737 HS90A_HUMAN (1-732): 0: 1087: 100.00		SIM1_HUMAN (16-659): 3.47e-146: 445: 26.05
+	Hs
		431903 HS90A_HUMAN (1-732): 0: 1087: 100.00		HIF1A_HUMAN (6-651): 9.51e-145: 443: 34.01
+	Mm
		432429 HS90A_MOUSE (1-732): 0: 1083: 97.82		SIM1_MOUSE (16-659): 1.49e-146: 446: 25.79
+	Mm
		432431 HS90A_MOUSE (1-732): 0: 1083: 97.82		HIF1A_MOUSE (6-662): 1.74e-145: 445: 32.63
+	Hs
		432201 HS90A_HUMAN (1-732): 0: 1087: 100.00		EPAS1_HUMAN (1-663): 3.7e-143: 440: 34.83
+	Hs
		438165 HS90B_HUMAN (19-732): 0: 1059: 86.13		SIM2_HUMAN (16-666): 1.85e-151: 455: 26.46
+	Hs
		438217 HS90B_HUMAN (19-732): 0: 1059: 86.13		HIF1A_HUMAN (6-651): 9.51e-145: 443: 34.01
+	Hs
		431556 HS90A_HUMAN (1-732): 0: 1087: 100.00		ARNT_HUMAN (4-604): 2.12e-126: 394: 18.64
+	Hs
		126097 HS90A_HUMAN (1-732): 0: 1087: 100.00		BMAL1_HUMAN (7-509): 7.37e-119: 370: 17.84
+	Hs
		431594 HS90A_HUMAN (1-732): 0: 1087: 100.00		AHR_HUMAN (3-661): 2.9e-112: 359: 17.47
+	Mm
		432410 HS90A_MOUSE (1-732): 0: 1083: 97.82		AHR_MOUSE (3-669): 3.68e-101: 330: 18.30
+	Rn
		783943 HS90A_RAT (1-732): 0: 1085: 97.95		AHR_RAT (3-669): 4.51e-100: 327: 17.66
+	Hs
		432199 HS90A_HUMAN (1-732): 0: 1087: 100.00		NPAS2_HUMAN (6-668): 1.47e-96: 317: 17.02
+	Mm
		513659 HS90B_MOUSE (19-732): 0: 1063: 86.98		AHR_MOUSE (3-669): 3.68e-101: 330: 18.30
+	Hs
		438468 HS90B_HUMAN (19-732): 0: 1059: 86.13		NPAS1_HUMAN (12-464): 5e-104: 330: 27.36
+	Dm
		1096504 Q9VAY2_DROME (15-700): 0: 537: 46.13		SIMA_DROME (5-626): 3.39e-100: 337: 25.08