HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: PRC2C (Q9Y520)
Protein PRRC2C (BAT2 domain-containing protein 1) (HBV X-transactivated gene 2 protein) (HBV XAg-transactivated protein 2) (HLA-B-associated transcript 2-like 2) (Proline-rich and coiled-coil-containing protein 2C)
Gene: PRRC2C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34349018, 35235311
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 2896
+	Hs
		431504 HS90A_HUMAN (1-732): 0: 1087: 100.00		MUC1_HUMAN (1225-2237): 6.18e-39: 162: 13.66
+	Hs
		432216 HS90A_HUMAN (1-732): 0: 1087: 100.00		DIDO1_HUMAN (88-631): 5.4e-37: 156: 16.09
+	Hs
		438458 HS90B_HUMAN (19-732): 0: 1059: 86.13		MINT_HUMAN (22-1891): 2.31e-43: 178: 9.12
+	Hs
		437983 HS90B_HUMAN (19-732): 0: 1059: 86.13		PRC2A_HUMAN (1183-2870): 8.38e-21: 103: 8.16
+	Hs
		432177 HS90A_HUMAN (1-732): 0: 1087: 100.00		CIC_HUMAN (57-1435): 3.5e-10: 68.5: 9.73
+	Hs
		432054 HS90A_HUMAN (1-732): 0: 1087: 100.00		MINK1_HUMAN (253-1019): 3.45e-10: 68.1: 11.95
+	Hs
		438364 HS90B_HUMAN (19-732): 0: 1059: 86.13		KMT2C_HUMAN (1901-2885): 8.54e-14: 80.6: 9.27
+	Hs
		438449 HS90B_HUMAN (19-732): 0: 1059: 86.13		CIC_HUMAN (57-1435): 3.5e-10: 68.5: 9.73
+	Hs
		438348 HS90B_HUMAN (19-732): 0: 1059: 86.13		MINK1_HUMAN (253-1019): 3.45e-10: 68.1: 11.95
+	Sc
		366285 HSP82_YEAST (16-732): 0: 907: 60.08		SEC31_YEAST (1809-2249): 1.42e-11: 72.8: 14.56
+	Sc
		543728 HSC82_YEAST (16-732): 0: 902: 59.39		SEC31_YEAST (1809-2249): 1.42e-11: 72.8: 14.56