HitPredict

Interactor 1: HNRPC (P07910)
Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1/C2)
Gene: HNRNPC

Interactor 2: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	16217013, 28977666
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PHD~RRM_1
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling GO:0016020 - membrane and 1 others more... GO:0032991 - protein-containing complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 306 Hs			1 1912
+	Hs
		71123 HNRC2_HUMAN (1-306): 2.65e-80: 247: 84.64		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		432675 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1059741 RB15B_HUMAN (9-292): 7.28e-31: 124: 12.03		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		71106 HNRC2_HUMAN (1-306): 2.65e-80: 247: 84.64		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		925038 TRA2B_HUMAN (4-164): 1.14e-27: 110: 21.77		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		951965 SRSF3_HUMAN (9-93): 1.72e-26: 104: 30.68		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1059804 RBM14_HUMAN (17-130): 2.17e-11: 66.5: 21.74		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1028915 SRSF6_HUMAN (17-92): 6.5e-10: 61.1: 30.26		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		925018 TRA2B_HUMAN (4-164): 1.14e-27: 110: 21.77		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		951935 SRSF3_HUMAN (9-93): 1.72e-26: 104: 30.68		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018647 RBM14_HUMAN (17-130): 2.17e-11: 66.5: 21.74		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018455 SRSF6_HUMAN (17-92): 6.5e-10: 61.1: 30.26		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		71039 HNRC2_HUMAN (1-306): 2.65e-80: 247: 84.64		SMCA5_HUMAN (578-1624): 0: 791: 26.01
+	Hs
		71074 HNRC2_HUMAN (1-306): 2.65e-80: 247: 84.64		SMCA1_HUMAN (617-1597): 0: 779: 27.44
+	Hs
		432940 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Hs
		1336309 RALY_HUMAN (2-298): 3.88e-63: 203: 40.19		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Hs
		229450 SRS12_HUMAN (8-190): 2.14e-34: 127: 20.94		SMCA5_HUMAN (578-1624): 0: 791: 26.01
+	Hs
		151398 SRSF3_HUMAN (9-93): 1.72e-26: 104: 30.68		CHD1_HUMAN (491-1733): 0: 734: 27.99