HitPredict

Interactor 1: HNRPC (P07910)
Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1/C2)
Gene: HNRNPC

Interactor 2: SRSF7 (Q16629)
Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)
Gene: SRSF7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008380 - RNA splicing and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 306 Hs			1 238
+	Hs
		241255 HNRC1_HUMAN (1-306): 2.22e-87: 265: 86.93		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		432618 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		NCBP2_HUMAN (10-114): 8.08e-26: 100: 23.42
+	Hs
		432507 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		71195 HNRC2_HUMAN (1-306): 2.65e-80: 247: 84.64		SRS12_HUMAN (1-218): 8.5e-28: 108: 32.60
+	Hs
		432657 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33
+	Hs
		432668 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65
+	Hs
		71066 HNRC2_HUMAN (1-306): 2.65e-80: 247: 84.64		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		241260 HNRC1_HUMAN (1-306): 2.22e-87: 265: 86.93		PAB4L_HUMAN (12-95): 5.81e-17: 80.5: 26.97
+	Hs
		432527 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Hs
		432886 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		RBM4B_HUMAN (12-89): 4.32e-17: 81: 32.05
+	Hs
		432518 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		PAB4L_HUMAN (12-95): 5.81e-17: 80.5: 26.97
+	Hs
		1084447 RALY_HUMAN (2-298): 3.88e-63: 203: 40.19		SRSF7_HUMAN (1-238): 6.03e-28: 108: 100.00
+	Hs
		432789 RALYL_HUMAN (3-284): 4.85e-66: 210: 52.23		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		432751 Q53GL6_HUMAN (2-298): 5.63e-63: 203: 40.06		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		432988 RALY_HUMAN (2-298): 3.88e-63: 203: 40.19		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Mm
		665756 RALY_MOUSE (3-300): 1.41e-66: 212: 42.19		PABP1_MOUSE (6-97): 2.51e-19: 88.2: 22.11
+	Hs
		952174 RALY_HUMAN (2-298): 3.88e-63: 203: 40.19		SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33
+	Hs
		516734 RALY_HUMAN (2-298): 3.88e-63: 203: 40.19		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Hs
		952060 SRS12_HUMAN (8-190): 2.14e-34: 127: 20.94		SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33
+	Hs
		992863 SRS12_HUMAN (8-190): 2.14e-34: 127: 20.94		SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65