HitPredict

Interactor 1: HNRPC (P07910)
Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1/C2)
Gene: HNRNPC

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0008380 - RNA splicing
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 306 Hs			1 582
+	Hs
		241312 HNRC1_HUMAN (1-306): 2.22e-87: 265: 86.93		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1116414 SRS12_HUMAN (8-190): 2.14e-34: 127: 20.94		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1116392 RMXL3_HUMAN (17-192): 1.81e-28: 117: 23.28		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		432527 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		241336 HNRC1_HUMAN (1-306): 2.22e-87: 265: 86.93		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		241260 HNRC1_HUMAN (1-306): 2.22e-87: 265: 86.93		PAB4L_HUMAN (1-203): 9.24e-35: 136: 11.85
+	Hs
		432836 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		241347 HNRC1_HUMAN (1-306): 2.22e-87: 265: 86.93		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Hs
		432518 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		PAB4L_HUMAN (1-203): 9.24e-35: 136: 11.85
+	Hs
		432856 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Mm
		665756 RALY_MOUSE (3-300): 1.41e-66: 212: 42.19		PABP1_MOUSE (1-405): 3.35e-40: 156: 10.05
+	Hs
		516734 RALY_HUMAN (2-298): 3.88e-63: 203: 40.19		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		1268191 RALY_HUMAN (2-298): 3.88e-63: 203: 40.19		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		241318 HNRC1_HUMAN (1-306): 2.22e-87: 265: 86.93		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		1288645 RALY_HUMAN (2-298): 3.88e-63: 203: 40.19		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Hs
		432773 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		432733 HNRPC_HUMAN (1-306): 1.06e-83: 256: 100.00		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		1263443 SRS12_HUMAN (8-190): 2.14e-34: 127: 20.94		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		516451 TRA2B_HUMAN (4-164): 1.14e-27: 110: 21.77		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Mm
		857303 TRA2B_MOUSE (4-164): 1.14e-27: 110: 21.77		TIA1_MOUSE (120-325): 5.06e-24: 106: 13.94