HitPredict

Interactor 1: YES (P07947)
Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)
Gene: YES1

Interactor 2: KHDR1 (Q07666)
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68)
Gene: KHDRBS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.665

Property	Details
Experiments	22745667, 15190072, unassigned1973
Identification Methods	unspecified method, fluorescent resonance energy transfer, affinity chromatography technology, enzymatic study, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 443
+	Mm
		980964 YES_MOUSE (1-543): 0: 601: 95.95		KHDR1_MOUSE (1-443): 0: 514: 94.36
+	Mm
		403437 SRC_MOUSE (1-543): 0: 598: 73.67		KHDR1_MOUSE (1-443): 0: 514: 94.36
+	Hs
		522933 SRC_HUMAN (1-543): 0: 601: 74.22		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Mm
		763394 FYN_MOUSE (1-543): 0: 582: 71.98		KHDR1_MOUSE (1-443): 0: 514: 94.36
+	Hs
		412149 FYN_HUMAN (1-543): 0: 582: 72.16		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		454827 FGR_HUMAN (1-542): 0: 562: 67.10		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		442815 HCK_HUMAN (1-541): 0: 544: 57.49		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		411689 LCK_HUMAN (83-541): 0: 540: 60.78		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Mm
		639447 LYN_MOUSE (1-541): 1.19e-179: 517: 53.14		KHDR1_MOUSE (1-443): 0: 514: 94.36
+	Hs
		433719 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		789110 FRK_HUMAN (71-535): 1.11e-172: 499: 48.25		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		986367 BTK_HUMAN (4-537): 1.03e-165: 487: 31.35		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		991758 PTK6_HUMAN (88-536): 9.35e-164: 474: 42.73		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		991737 ITK_HUMAN (7-532): 1.69e-157: 464: 31.54		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Mm
		763412 FYN_MOUSE (1-543): 0: 582: 71.98		KHDR2_MOUSE (100-443): 8.36e-126: 370: 61.65
+	Hs
		433822 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		KHDR2_HUMAN (99-443): 5.18e-130: 381: 60.62
+	Hs
		1046410 PTK6_HUMAN (88-536): 9.35e-164: 474: 42.73		KHDR2_HUMAN (99-443): 5.18e-130: 381: 60.62
+	Dm
		337713 SRC64_DROME (1-542): 1.76e-173: 503: 46.57		Q9W255_DROME (59-398): 6.04e-96: 295: 32.35
+	Hs
		789069 ABL2_HUMAN (9-543): 9.27e-166: 503: 37.96		SF01_HUMAN (82-301): 6.63e-54: 192: 21.33
+	Hs
		337484 ABL1_HUMAN (41-543): 5.93e-161: 489: 39.10		SF01_HUMAN (82-301): 6.63e-54: 192: 21.33