HitPredict

Interactor 1: YES (P07947)
Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)
Gene: YES1

Interactor 2: H90B4 (Q58FF6)
Putative heat shock protein HSP 90-beta 4
Gene: HSP90AB4P

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	28514442, 33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 505
+	Hs
		433218 YES_HUMAN (1-543): 0: 617: 100.00		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		431433 YES_HUMAN (1-543): 0: 617: 100.00		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		437847 SRC_HUMAN (1-543): 0: 601: 74.22		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		431481 SRC_HUMAN (1-543): 0: 601: 74.22		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		411949 FYN_HUMAN (1-543): 0: 582: 72.16		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		411945 FYN_HUMAN (1-543): 0: 582: 72.16		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		437823 FGR_HUMAN (1-542): 0: 562: 67.10		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		412222 FYN_HUMAN (1-543): 0: 582: 72.16		H90B4_HUMAN (1-505): 0: 644: 100.00
+	Hs
		431451 FGR_HUMAN (1-542): 0: 562: 67.10		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		437817 HCK_HUMAN (1-541): 0: 544: 57.49		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		411556 LCK_HUMAN (83-541): 0: 540: 60.78		HS90B_HUMAN (1-504): 0: 671: 69.93
+	Hs
		431445 HCK_HUMAN (1-541): 0: 544: 57.49		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Dm
		365472 SRC42_DROME (35-541): 0: 527: 53.79		HSP83_DROME (1-504): 0: 669: 57.69
+	Hs
		411551 LCK_HUMAN (83-541): 0: 540: 60.78		HS90A_HUMAN (1-504): 0: 655: 62.96
+	Hs
		411978 FYN_HUMAN (1-543): 0: 582: 72.16		ENPL_HUMAN (1-504): 0: 597: 35.70
+	Hs
		433379 YES_HUMAN (1-543): 0: 617: 100.00		H90B3_HUMAN (1-504): 3.09e-143: 426: 58.87
+	Hs
		412223 FYN_HUMAN (1-543): 0: 582: 72.16		H90B3_HUMAN (1-504): 3.09e-143: 426: 58.87
+	Hs
		454838 FGR_HUMAN (1-542): 0: 562: 67.10		H90B3_HUMAN (1-504): 3.09e-143: 426: 58.87
+	Hs
		442841 HCK_HUMAN (1-541): 0: 544: 57.49		H90B3_HUMAN (1-504): 3.09e-143: 426: 58.87
+	Hs
		411751 LCK_HUMAN (83-541): 0: 540: 60.78		H90B3_HUMAN (1-504): 3.09e-143: 426: 58.87