HitPredict

Interactor 1: YES (P07947)
Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)
Gene: YES1

Interactor 2: CXB7 (Q6PEY0)
Gap junction beta-7 protein (Connexin-25) (Cx25)
Gene: GJB7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 223
+	Hs
		433245 YES_HUMAN (1-543): 0: 617: 100.00		CXA1_HUMAN (2-214): 1.78e-100: 297: 39.51
+	Hs
		412232 FYN_HUMAN (1-543): 0: 582: 72.16		CXB7_HUMAN (1-223): 7.41e-113: 323: 100.00
+	Hs
		522752 SRC_HUMAN (1-543): 0: 601: 74.22		CXA1_HUMAN (2-214): 1.78e-100: 297: 39.51
+	Rn
		435433 SRC_RAT (1-543): 0: 600: 73.67		CXA1_RAT (2-214): 6.16e-100: 296: 39.10
+	Mm
		403416 SRC_MOUSE (1-543): 0: 598: 73.67		CXA1_MOUSE (2-214): 7.57e-100: 296: 39.10
+	Hs
		433414 YES_HUMAN (1-543): 0: 617: 100.00		CXD3_HUMAN (2-205): 1.92e-82: 249: 35.35
+	Hs
		433835 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		CXB7_HUMAN (1-223): 7.41e-113: 323: 100.00
+	Hs
		337394 ABL1_HUMAN (41-543): 5.93e-161: 489: 39.10		CXA8_HUMAN (2-218): 2.15e-116: 340: 42.80
+	Hs
		566936 EPHA3_HUMAN (3-535): 2.01e-156: 473: 25.84		CXA1_HUMAN (2-214): 1.78e-100: 297: 39.51
+	Hs
		566985 EPHA4_HUMAN (4-542): 2.62e-155: 470: 25.00		CXA1_HUMAN (2-214): 1.78e-100: 297: 39.51
+	Hs
		433886 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		CXD3_HUMAN (2-205): 1.92e-82: 249: 35.35