HitPredict

Interactor 1: YES (P07947)
Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)
Gene: YES1

Interactor 2: ANR12 (Q6UB98)
Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein)
Gene: ANKRD12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26186194
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~SH3_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 2062
+	Hs
		412234 FYN_HUMAN (1-543): 0: 582: 72.16		ANR12_HUMAN (1-2062): 0: 900: 100.00
+	Hs
		434072 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		ANR50_HUMAN (100-965): 2.04e-48: 193: 10.39
+	Dm
		337696 SRC64_DROME (1-542): 1.76e-173: 503: 46.57		TNKS_DROME (155-600): 8.09e-42: 171: 15.17
+	Hs
		411885 LCK_HUMAN (83-541): 0: 540: 60.78		KDIS_HUMAN (193-392): 8.81e-29: 128: 17.50
+	Hs
		411877 LCK_HUMAN (83-541): 0: 540: 60.78		RAI14_HUMAN (85-960): 1.59e-24: 114: 10.77
+	Hs
		434071 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		KDIS_HUMAN (193-392): 8.81e-29: 128: 17.50
+	Hs
		434045 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		RAI14_HUMAN (85-960): 1.59e-24: 114: 10.77
+	Hs
		665439 EPHA3_HUMAN (3-535): 2.01e-156: 473: 25.84		KDIS_HUMAN (193-392): 8.81e-29: 128: 17.50
+	Hs
		337406 ABL1_HUMAN (41-543): 5.93e-161: 489: 39.10		DAPK1_HUMAN (11-173): 7.43e-19: 96.1: 7.83
+	Hs
		433986 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		UACA_HUMAN (317-1035): 9.1e-09: 63.1: 13.06