HitPredict

Interactor 1: YES (P07947)
Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)
Gene: YES1

Interactor 2: CC186 (Q7Z3E2)
Coiled-coil domain-containing protein 186 (CTCL tumor antigen HD-CL-01/L14-2)
Gene: CCDC186

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 898
+	Hs
		411758 LCK_HUMAN (83-541): 0: 540: 60.78		MRCKA_HUMAN (133-734): 1.26e-93: 326: 20.39
+	Hs
		433818 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		MRCKA_HUMAN (133-734): 1.26e-93: 326: 20.39
+	Hs
		411908 LCK_HUMAN (83-541): 0: 540: 60.78		MRCKB_HUMAN (137-740): 6.18e-72: 261: 17.72
+	Hs
		434101 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		MRCKB_HUMAN (137-740): 6.18e-72: 261: 17.72
+	Hs
		523231 SRC_HUMAN (1-543): 0: 601: 74.22		MYH4_HUMAN (2-888): 2.82e-38: 157: 10.43
+	Hs
		111443 J3QRU1_HUMAN (1-543): 0: 617: 100.00		MYH9_HUMAN (478-896): 3.7e-16: 85.9: 11.42
+	Hs
		433272 YES_HUMAN (1-543): 0: 617: 100.00		MYH9_HUMAN (478-896): 3.7e-16: 85.9: 11.42
+	Hs
		411983 FYN_HUMAN (1-543): 0: 582: 72.16		DESP_HUMAN (42-686): 1.29e-18: 93.9: 11.33
+	Hs
		412058 FYN_HUMAN (1-543): 0: 582: 72.16		MYH9_HUMAN (478-896): 3.7e-16: 85.9: 11.42
+	Hs
		411581 LCK_HUMAN (83-541): 0: 540: 60.78		DESP_HUMAN (42-686): 1.29e-18: 93.9: 11.33
+	Hs
		433558 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		DESP_HUMAN (42-686): 1.29e-18: 93.9: 11.33
+	Hs
		433620 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		MYH9_HUMAN (478-896): 3.7e-16: 85.9: 11.42
+	Hs
		724720 BLK_HUMAN (66-538): 5.05e-174: 502: 59.07		MYH9_HUMAN (478-896): 3.7e-16: 85.9: 11.42
+	Hs
		665375 EPHA3_HUMAN (3-535): 2.01e-156: 473: 25.84		MYH9_HUMAN (478-896): 3.7e-16: 85.9: 11.42