HitPredict

Interactor 1: YES (P07947)
Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)
Gene: YES1

Interactor 2: CEP83 (Q9Y592)
Centrosomal protein of 83 kDa (Cep83) (Coiled-coil domain-containing protein 41) (Renal carcinoma antigen NY-REN-58)
Gene: CEP83

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 701
+	Hs
		411908 LCK_HUMAN (83-541): 0: 540: 60.78		MRCKB_HUMAN (122-689): 2.15e-49: 189: 16.10
+	Hs
		111443 J3QRU1_HUMAN (1-543): 0: 617: 100.00		MYH9_HUMAN (1-610): 2.56e-22: 105: 12.75
+	Hs
		433272 YES_HUMAN (1-543): 0: 617: 100.00		MYH9_HUMAN (1-610): 2.56e-22: 105: 12.75
+	Hs
		523231 SRC_HUMAN (1-543): 0: 601: 74.22		MYH4_HUMAN (20-700): 2.92e-27: 120: 11.35
+	Hs
		434101 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		MRCKB_HUMAN (122-689): 2.15e-49: 189: 16.10
+	Hs
		433749 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		ROCK1_HUMAN (25-629): 3.74e-49: 188: 19.57
+	Hs
		412058 FYN_HUMAN (1-543): 0: 582: 72.16		MYH9_HUMAN (1-610): 2.56e-22: 105: 12.75
+	Hs
		412287 FYN_HUMAN (1-543): 0: 582: 72.16		MY18A_HUMAN (131-670): 4.88e-16: 84.7: 12.68
+	Hs
		411983 FYN_HUMAN (1-543): 0: 582: 72.16		DESP_HUMAN (53-625): 4.9e-10: 65.3: 16.24
+	Hs
		433620 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		MYH9_HUMAN (1-610): 2.56e-22: 105: 12.75
+	Hs
		411758 LCK_HUMAN (83-541): 0: 540: 60.78		MRCKA_HUMAN (82-594): 9.08e-13: 74.2: 16.67
+	Hs
		724720 BLK_HUMAN (66-538): 5.05e-174: 502: 59.07		MYH9_HUMAN (1-610): 2.56e-22: 105: 12.75
+	Hs
		411581 LCK_HUMAN (83-541): 0: 540: 60.78		DESP_HUMAN (53-625): 4.9e-10: 65.3: 16.24
+	Hs
		433818 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		MRCKA_HUMAN (82-594): 9.08e-13: 74.2: 16.67
+	Hs
		433558 LYN_HUMAN (1-541): 3.82e-179: 515: 53.69		DESP_HUMAN (53-625): 4.9e-10: 65.3: 16.24
+	Hs
		665375 EPHA3_HUMAN (3-535): 2.01e-156: 473: 25.84		MYH9_HUMAN (1-610): 2.56e-22: 105: 12.75