HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: EPB41 (P11171)
Protein 4.1 (P4.1) (4.1R) (Band 4.1) (EPB4.1) (Erythrocyte membrane protein band 4.1)
Gene: EPB41

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~PK_Tyr_Ser-Thr
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0009898 - cytoplasmic side of plasma membrane GO:0051219 - phosphoprotein binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 512 Hs			1 864
+	Hs
		434020 LYN_HUMAN (1-512): 0: 611: 100.00		E41L5_HUMAN (166-858): 2.25e-170: 513: 26.50
+	Hs
		434008 LYN_HUMAN (1-512): 0: 611: 100.00		E41L1_HUMAN (137-864): 2.16e-161: 494: 41.50
+	Hs
		411867 LCK_HUMAN (1-512): 0: 582: 63.62		E41L5_HUMAN (166-858): 2.25e-170: 513: 26.50
+	Hs
		411855 LCK_HUMAN (1-512): 0: 582: 63.62		E41L1_HUMAN (137-864): 2.16e-161: 494: 41.50
+	Hs
		434004 LYN_HUMAN (1-512): 0: 611: 100.00		E41LB_HUMAN (210-838): 6.88e-143: 447: 27.57
+	Hs
		299230 LYN_HUMAN (1-512): 0: 611: 100.00		FARP2_HUMAN (167-772): 3.94e-134: 428: 27.14
+	Hs
		412035 FYN_HUMAN (1-510): 0: 576: 54.12		PTN4_HUMAN (183-691): 3.51e-141: 443: 32.51
+	Hs
		434097 LYN_HUMAN (1-512): 0: 611: 100.00		FARP1_HUMAN (168-772): 1.31e-123: 400: 27.71
+	Hs
		433617 LYN_HUMAN (1-512): 0: 611: 100.00		MERL_HUMAN (195-763): 8.67e-121: 380: 19.69
+	Hs
		523010 SRC_HUMAN (1-510): 0: 580: 51.97		PTN21_HUMAN (190-862): 1.12e-124: 406: 20.32
+	Hs
		433618 LYN_HUMAN (1-512): 0: 611: 100.00		RADI_HUMAN (206-762): 2.33e-118: 373: 20.55
+	Hs
		411904 LCK_HUMAN (1-512): 0: 582: 63.62		FARP1_HUMAN (168-772): 1.31e-123: 400: 27.71
+	Hs
		433240 YES_HUMAN (1-510): 0: 572: 54.26		EZRI_HUMAN (206-762): 1.18e-124: 389: 22.51
+	Hs
		337358 ABL1_HUMAN (32-509): 9.04e-172: 516: 37.88		PTN4_HUMAN (183-691): 3.51e-141: 443: 32.51
+	Hs
		523042 SRC_HUMAN (1-510): 0: 580: 51.97		FRMD5_HUMAN (200-673): 1.03e-118: 373: 31.11
+	Hs
		204599 LYN_HUMAN (1-512): 0: 611: 100.00		E41L2_HUMAN (506-864): 1.22e-27: 122: 34.44
+	Hs
		434091 LYN_HUMAN (1-512): 0: 611: 100.00		E41L3_HUMAN (596-833): 2.3e-10: 66.5: 21.67
+	Hs
		411899 LCK_HUMAN (1-512): 0: 582: 63.62		E41L3_HUMAN (596-833): 2.3e-10: 66.5: 21.67
+	Hs
		523221 SRC_HUMAN (1-510): 0: 580: 51.97		E41L3_HUMAN (596-833): 2.3e-10: 66.5: 21.67
+	Hs
		412416 FYN_HUMAN (1-510): 0: 576: 54.12		E41L3_HUMAN (596-833): 2.3e-10: 66.5: 21.67