HitPredict

Interactor 1: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Interactor 2: FCG2A (P12318)
Low affinity immunoglobulin gamma Fc region receptor II-a (IgG Fc receptor II-a) (CDw32) (Fc-gamma RII-a) (Fc-gamma-RIIa) (FcRII-a) (CD antigen CD32)
Gene: FCGR2A

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.578

Property	Details
Experiments	9268059
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, protein kinase assay
Interaction Type	physical association, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 512 Hs			1 317
+	Hs
		522812 SRC_HUMAN (1-510): 0: 580: 51.97		FCG2C_HUMAN (1-317): 2.11e-73: 230: 85.17
+	Hs
		412048 FYN_HUMAN (1-510): 0: 576: 54.12		FCG2C_HUMAN (1-317): 2.11e-73: 230: 85.17
+	Hs
		411560 LCK_HUMAN (1-512): 0: 582: 63.62		FCG3A_HUMAN (16-255): 1.34e-61: 198: 43.03
+	Hs
		519400 SRC_HUMAN (1-510): 0: 580: 51.97		FCERA_HUMAN (20-247): 4.5e-59: 191: 32.02
+	Hs
		433569 LYN_HUMAN (1-512): 0: 611: 100.00		CD22_HUMAN (31-309): 1.51e-30: 123: 16.61
+	Mm
		639452 LYN_MOUSE (1-512): 0: 612: 96.09		FCRL5_MOUSE (22-294): 3.17e-27: 113: 15.72
+	Hs
		434081 LYN_HUMAN (1-512): 0: 611: 100.00		TUTLB_HUMAN (28-309): 3.52e-25: 107: 14.84
+	Mm
		435878 HCK_MOUSE (1-512): 0: 592: 69.92		FCGR1_MOUSE (7-311): 3.47e-26: 108: 17.28
+	Hs
		433742 LYN_HUMAN (1-512): 0: 611: 100.00		PTK7_HUMAN (124-313): 1.3e-18: 88.3: 10.68
+	Hs
		442771 HCK_HUMAN (1-512): 0: 595: 70.70		FCGR1_HUMAN (30-277): 9.95e-25: 104: 16.54
+	Dm
		219802 ABL_DROME (3-508): 3.3e-170: 523: 36.36		O44924_DROME (3-306): 2.92e-48: 175: 12.77
+	Hs
		434111 LYN_HUMAN (1-512): 0: 611: 100.00		ROBO1_HUMAN (1-115): 1.09e-15: 79.8: 17.46
+	Hs
		434019 LYN_HUMAN (1-512): 0: 611: 100.00		ROBO2_HUMAN (1-115): 1.43e-15: 79.5: 14.96
+	Hs
		523211 SRC_HUMAN (1-510): 0: 580: 51.97		TUTLB_HUMAN (28-309): 3.52e-25: 107: 14.84
+	Hs
		433610 LYN_HUMAN (1-512): 0: 611: 100.00		FCG2B_HUMAN (113-315): 1.08e-12: 69.4: 16.02
+	Hs
		433507 YES_HUMAN (1-510): 0: 572: 54.26		TUTLB_HUMAN (28-309): 3.52e-25: 107: 14.84
+	Hs
		433947 LYN_HUMAN (1-512): 0: 611: 100.00		KIRR1_HUMAN (127-315): 3.55e-11: 66: 9.01
+	Hs
		522811 SRC_HUMAN (1-510): 0: 580: 51.97		FCG2B_HUMAN (113-315): 1.08e-12: 69.4: 16.02
+	Hs
		412047 FYN_HUMAN (1-510): 0: 576: 54.12		FCG2B_HUMAN (113-315): 1.08e-12: 69.4: 16.02
+	Hs
		789014 TEC_HUMAN (35-505): 1.09e-160: 472: 35.48		TUTLB_HUMAN (28-309): 3.52e-25: 107: 14.84